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KMID : 0942820120110020158
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Journal of Korean Brain Tumor Society
2012 Volume.11 No. 2 p.158 ~ p.162
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Distant Wounded Glioma Syndrome in a Multiple Primary Cancer Patient Accompanying with Glioblastoma Multiforme
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Choi Hyun-Jun
Choi Chan-Young
Lee Chae-Heuck
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Abstract
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It has been well known that postoperative hemorrhage can occur in the surgical bed, especially after incomplete resection of highly vascularized tumor, such as glioblastoma. A 55-year old female patient who has breast cancer and multifocal glioblastoma mimicking brain metastasis together showed postoperative hemorrhage in the surgical bed and spontaneous postoperative bleeding of remote tumor site, which was called distant wounded glioma syndrome. In multifocal glioblastoma, histological confirmation may be necessary to differentiate from brain metastasis, even in the presence of a known primary malignancy of other organ. Perioperative careful examination for patient’s coagulation system may also be necessary to prevent or treat distant wounded glioma syndrome.
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KEYWORD
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Glioblastoma, Multiple primary neoplasm, Metastasis
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